Product Description

MMP2 Mouse Monoclonal Antibody (1H1)

Sizes: 50μL, 100μL

Catalogue Numbers: RA11672-50, RA11672-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: matrix metallopeptidase 2 (MMP2) Homo sapiens This gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis. Mutations in this gene have been associated with Win

Reactivity: Human, Rat, Mouse

Host: Mouse

Applications: IHC-p, IF(paraffin section)

Alternate Names: MMP2

Clonality: Monoclonal

Dilution: IHC 1:100-200

Storage: -20°C/1 year

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Human Gene ID: 4313

Protein Molecular Weight（KDa): 64，72

Molecular Weight: 64，72

Research Use Only