MMP24 Polyclonal Antibody - BT-AP11405

MMP24 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP11405-20, BT-AP11405-50, BT-AP11405-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. Unlike most MMPs, which are secreted, this protease is a member of the membrane-type MMP (MT-MMP) subfamily, contains a transmembrane domain and is expressed at the cell surface. Substrates of this protease include the proteins cadherin 2 and matrix metallopeptidase 2 (also known as 72 kDa type IV collagenase).

Research Areas: Cancer; Cell biology; Signal transduction; Neuroscience

Target Protein: MMP24

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Matrix metalloproteinase-24

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q9Y5R2; Mouse: Q9R0S2; Rat: Q99PW6

Synonyms: Matrix metalloproteinase-24;MMP-24;EC 3.4.24.-;Membrane-type matrix metalloproteinase 5;MT-MMP 5;MTMMP5;Membrane-type-5 matrix metalloproteinase;MT5-MMP;MT5MMP [Cleaved into: Processed

GeneID: Human: 10893

Research Use Only