Product Description

MMP8 Rabbit Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS40179-50, BS40179-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellμlar matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellμlar proteinases. However, the enzyme encoded by this gene is stored in secondary granμles within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Category: Primary Antibody

Reactivity: Human Mouse Rat

Host: Rabbit

Applications: WB, IHC, ICC/IF, IP, FC

Alternate Names: HNC, CLG1, MMP-8, PMNL-CL, COLLAGENASE I, NEUTROPHIL, matrix metalloproteinase 8,

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: A synthesized peptide derived from human MMP8

Dilution: WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50

Purification: Affinity-chromatography

Specificity: MMP8 Antibody detects endogenous levels of MMP8

Molecular Weight: 53kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P22894

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Research Use Only