MMP9 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-63483-60, E-AB-63483-120, E-AB-63483-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: MMP9
Target Synonym: MMP9; CLG4B; GELB; MANDP2; MMP-9
Research Areas: Cancer, Cell Biology, Cardiovascular, Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: IHC
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P14780
Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.
Concentration: 1mg/mL
Immunogen: A synthetic peptide of human MMP9 (NP_004985.2).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: IHC 1:100-1:200
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only