Product Description

MOBP Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65670-50, BS65670-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The gene encoding MOBP a member of the central nervous system myelin-constituting proteins, maps to chromosome 3p22.2. MOBP has many splice variants that share a 68 amino acid N-terminal domain. MOBP-71, MOBP-81A, MOBP-99, and MOBP-169 are MOBP splice variants that contain exon 8b, which is similar to myelin basic protein (MBP) mRNA RTS, however MOBP-69, MOBP-81B, and MOBP-170 lack this exon. The splice variants that contain exon 8b are expressed in myelin, while those lacking exon 8b are retained in the oligodendrocyte soma. Exon 8b-containing variants are directed to sites of myelin sheath assembly by exon 8b, where they play a structural role in myelin formation. Splice variants lacking exon 8b likely play a cellμlar and/or regμlatory role. MOBP is implicated in mμltiple sclerosis (MS), a human demyelinating disease, and in allergic encephalomyelitis in rodents.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep

Host: Rabbit

Applications: IHC-P

Alternate Names: MGC87379, Myelin associated oligodendrocyte basic protein, MOBP_HUMAN.

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human MOBP

Dilution: IHC-P=1:100-500

Purification: affinity purified by Protein A

Specificity: MOBP Polyclonal Antibody detects endogenous levels of MOBP protein.

Molecular Weight: 21kD

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q13875

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only