Moesin Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS90876-50, BS90876-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P26038(Human) P26041(Mouse) O35763(Rat)
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, ICC/IF, IHC, IP, , FC
All Applications: WB:1:1,000-1:2,000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100
Background: Ezrin, Moesin and Radixin belong to a family of highly homologous Actin-associated proteins that are localized just beneath the plasma membrane. These proteins are believed to be involved in the mediation of interactions between cytoskeletal and membrane proteins. Ezrin serves as a major cytoplasmic substrate of various protein-tyrosine kinases, including the epidermal growth factor receptor. Ezrin has also been identified as a cAMP-dependent protein kinase (A-kinase) anchoring protein and designated AKAP78. Moesin and Radixin share more than 70% homology with Ezrin and are co-expressed within various cell types. Despite the high degree of homology, the three proteins exhibit a distinct receptor-specific pattern of phosphorylation.
Purification and Purity: ProA affinity purified
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: Moesin polyclonal antibody detects endogenous levels of Moesin protein.
Bioworld Molecular Weight: 68 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of Moesin on different lysates using anti-Moesin antibody at 1/1,000 dilution.
Positive control:
Lane 1: Raji
Lane 2: SH-SY-5Y, ICC staining Moesin in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Alternative Name: MSN, Epididymis luminal protein 70, HEL70, Membrane organizing extension spike protein, Membrane-organizing extension spike protein, MOES, Moesin, Moesin/anaplastic lymphoma kinase fusion protein, Msn, MSN/ALK fusion,
Immunogen: recombinant protein
Conjugate: Unconjugated
Modification: Unmodified