Product Description

MonoMethyl-p53 (Lys370) (4C7) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3325-50, MB3325-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P04637

Host: Mouse

Reactivity: Human, Rat, Mouse

Applications: IHC-P

All Applications: IHC: 1/50-1/100

Background: Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry analysis of paraffin-embedded Human Lung Carcinoma using MonoMethyl-p53 antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval.

Specificity: IgG1

Alternative Name: Cellular tumor antigen p53; Cys 51 stop; Tp53; Tumor protein p53

Immunogen: Synthetic peptide conjugated to KLH.

Conjugate: Unconjugated

Modification: Methylated