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Mouse Monoclonal Antibody to Human Cardiac Troponin I - 103-100

Mouse Monoclonal Antibody to Human Cardiac Troponin I - 103-100

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Mouse Monoclonal Antibody to Human Cardiac Troponin I

Size: 100 µg

Catalogue Number: 103-100

Citations, Manuals and MSDS Available upon request.

Immunogen: Human cardiac troponin I

Immunogen Description: Native, affinity purified human cardiac troponin I

Background: Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it, myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle (Wikipedia)

UniProt ID: P19429

Clonality: Mouse monoclonal

Clone: 1D12

Class: IgG1

Reactivity: human cardiac troponin I

Dissociation constant (KD): 4.3 x 10-10 M

Application: ELISA, WB

Protocol: ELISA, 0.05-0.1 μg/ml; WB, 0.2 to 0.5 μg/ml

Purification: Protein G purification

Buffer: PBS pH 7.4; 0.1% NaN3

Shipping: This product is shipped in non-frozen liquid form in ambient conditions

Storage: Store at –20 to -70°C upon receipt. Divide antibody into aliquots prior usage. Avoid multiple freeze-thaw cycles

Research Use Only