Product Description

MP68 Polyclonal Antibody

Catalogue Numbers: BS61111-50, BS61111-100

Sizes: 50µl, 100µl

Alternative Name: 6.8 kDa mitochondrial proteolipid; MP68; C14orf2; PRO1574

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P56378

Host: Rabbit

Reactivity: Human, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: MP68, also known as PLPM or C14orf2 (chromosome 14 open reading frame 2), is a 58 amino acid mitochondrial protein that belongs to the small mitochondrial proteolipid family. The gene encoding MP68 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder α1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: MP68 polyclonal antibody detects endogenous levels of MP68 protein.

Bioworld Molecular Weight: ~ 9 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of MP68 pAb at 1:1000 dilution
Lane 1: The Brain tissue lysate of Rat(20ug)
Lane 2: HepG2 whole cell lysate(20ug)
Lane 3: HCT116 whole cell lysate(20ug)

Immunogen: A synthetic peptide corresponding to residues in Human MP68.

Conjugate: Unconjugated

Modification: Unmodified