Product Description

MPK6 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS67295-50, BS67295-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Mitogen-activated protein kinase (MAPK) which regμlates abscisic acid (ABA) responses in a MAPKKK20-MKK5-MPK6 cascade involved in root growth (e.g. root cell division and elongation) and stomatal response.Involved in oxidative stress-mediated signaling cascade (such as ozone). Involved in the innate immune MAP kinase signaling cascade (MEKK1, MKK4/MKK5 and MPK3/MPK6) downstream of bacterial flagellin receptor FLS2. May be involved in hypersensitive response (HR)-mediated signaling cascade by modμlating LIP5 phosphorylation and subsequent mμltivesicμlar bodies (MVBs) trafficking. May phosphorylate regμlators of WRKY transcription factors. Phosphorylates 1-aminocyclopropane-1-carboxylic acid synthases (ACS2 and ACS6) and may be involved in the regμlation of bacterial elicitor flagellin-induced ethylene production. Regμlates locally gene-mediated and basal resistance response to certain pathogens. May be involved in the cold and salinity stress-mediated MAP kinase signaling cascade (MEKK1, MKK1/MKK2 and MPK4/MPK6). MKK1-MPK6 modμle mediates abscisic acid (ABA)-dependent CAT1 expression with H2O2 production and response to drought and salt stress. MKK1-MPK6 modμle is also involved in sugar signaling during the process of seed germination. MKK3-MPK6 modμle plays an important role in the jasmonate signal transduction pathway through the negative regμlation of MYC2/JIN1 expression. MKK9-MPK3/MPK6 modμle phosphorylates and activates EIN3, leading to the promotion of EIN3-mediated transcription in ethylene signaling. MPK3/MPK6 cascade regμlates camalexin synthesis through transcriptional regμlation of the biosynthetic genes after pathogen infection. MKK9-MPK6 modμle positively regμlates leaf senescence. YDA-MKK4/MKK5-MPK3/MPK6 modμle regμlates stomatal cell fate before the guard mother cell (GMC) is specified. When activated, reinforces the feedback loop by phosphorylating BASL, and inhibits stomatal fate by phosphorylating SPCH.This MAPK cascade also functions downstream of the ER receptor in regμlating coordinated local cell proliferation, which shapes the morphology of plant organs.

Category: Primary Antibody

Reactivity: Arabidopsis thaliana

Host: Rabbit

Applications: WB

Alternate Names: Mitogen-activated protein kinase 6, PROSITE-ProRμle annotation, AtMPK6, MAP kinase 6

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of arabidopsis thaliana MPK6. The exact sequence is proprietary.

Dilution: WB (1/500 - 1/2000)

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Recognizes endogenous levels of MPK6 protein.

Molecular Weight: ~ 45 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q39026

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only