Product Description

Mre11 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11233-50, MB11233-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P49959

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100

Background: DNA double-strand breaks are generated by ionizing radiation and endogenously produced radicals, and they often are repaired through the RAD52 homologous recombination pathway. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 81 kDa; Observed MW: 81 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Mre11 in K562, rat Brain, C6, 3T3, Hela lysates using Mre11 antibody., Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Mre11 antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval.

Alternative Name: MRE11 homolog 1; Meiotic recombination 11 homolog A; MRE11 homolog A; MRE11A; HNGS1; MRE11

Immunogen: Recombinant protein of human Mre11

Conjugate: Unconjugated

Modification: Unmodified