MRG15 (R56) Polyclonal Antibody
Catalogue Numbers:BS2674-50, BS2674-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q9UBU8
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: IHC, IF
All Applications: IHC: 1:50~1:200
IF: 1:50~1:200
Background: MRG15 ia a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis and DNA repair.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Bioworld Molecular Weight: ~ 41 kDa
Specificity: MRG15 (R56) polyclonal antibody detects endogenous levels of MRG15 protein.
Note: For research use only, not for use in diagnostic procedure.
Alternative Name: Mortality factor 4-like protein 1; MORF-related gene 15 protein; Protein MSL3-1; Transcription factor-like protein MRG15; MORF4L1; MRG15; FWP006; HSPC008; HSPC061; PP368
Immunogen: Synthetic peptide, corresponding to amino acids 23-75 of Human MRG15.
Conjugate: Unconjugated
Modification: Unmodified