Product Description

MRGPRX1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS75201-50, BS75201-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Orphan receptor. Probably involved in the function of nociceptive neurons. May regμlate nociceptor function and/or development, including the sensation or modμlation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medμlla peptide 22 and BAM (8-22(PubMed:26582731. BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellμlar calcium in stably transfected cells. G(alphaq proteins are involved in the calcium-signaling pathway. Activated by the antimalarial drug, chloroquine. May mediate chloroquine-induced itch, in a histamine-independent manner.

Category: Primary Antibody

Reactivity: Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: MRGPRX1, GPCR, MGRG2, MRGX1, SNSR4

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human MRGPRX1(NP_671732.3).

Dilution: WB, 1:500 - 1:2000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Unmodification

Molecular Weight: 36kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q96LB2

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only