MRGRD rabbit pAb - ES11508

MRGRD rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES11508-50, ES11508-100

Citations, Manuals and MSDS Available upon request.

Background: function:May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca (2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G (q) and G (i)., similarity:Belongs to the G-protein coupled receptor 1 family. Mas subfamily., subcellular location:Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.,

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized peptide derived from part region of human protein

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 35kD

Human Gene ID: 116512

Human SWISS Prot NO: Q8TDS7

Subcellular Location: Cell membrane; Multi-pass membrane protein. Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.

Research Use Only