MRGX1 rabbit pAb - ES5449

MRGX1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES5449-50, ES5449-100

Citations, Manuals and MSDS Available upon request.

Background: function:Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G (alpha)q proteins are involved in the calcium-signaling pathway., similarity:Belongs to the G-protein coupled receptor 1 family. Mas subfamily., tissue specificity:Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.,

Alternate Name: MRGPRX1; MRGX1; SNSR3; SNSR4; Mas-related G-protein coupled receptor member X1; Sensory neuron-specific G-protein coupled receptor 3/4

Source: Rabbit

Applications: WB; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human MRGX1. AA range:271-320

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 36kD

Human Gene ID: 259249

Human SWISS Prot NO: Q96LB2

Subcellular Location: Cell membrane; Multi-pass membrane protein.

Research Use Only