MRGX2 rabbit pAb - ES11657

MRGX2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES11657-50, ES11657-100

Citations, Manuals and MSDS Available upon request.

Background: function:Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca (2+) but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G (q)-coupled., similarity:Belongs to the G-protein coupled receptor 1 family. Mas subfamily., tissue specificity:Has a limited expression profile, both peripheral and within the central nervous system, with highest levels in dorsal root ganglion.,

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from human protein . at AA range: 250-330

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 36kD

Human Gene ID: 117194

Human SWISS Prot NO: Q96LB1

Subcellular Location: Cell membrane; Multi-pass membrane protein.

Research Use Only