MRLC2 (phospho Ser20) rabbit pAb - ES5880

MRLC2 (phospho Ser20) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES5880-50, ES5880-100

Citations, Manuals and MSDS Available upon request.

Background: Myosin, a structural component of muscle, consists of two heavy chains and four light chains. The protein encoded by this gene is a myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads. The encoded protein binds calcium and is activated by myosin light chain kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Alternate Name: MYL9; MLC2; MRLC1; MYRL2; Myosin regulatory light polypeptide 9; 20 kDa myosin light chain; LC20; MLC-2C; Myosin RLC; Myosin regulatory light chain 2; smooth muscle isoform; Myosin regulatory light chain 9; Myosin regulatory light chain MRL

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human Myosin regulatory light chain 2 around the phosphorylation site of Ser18. AA range:3-52

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 18kD

Human Gene ID: 10398/10627

Human SWISS Prot NO: P24844

Subcellular Location: Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Colocalizes with F-actin, MYH9 and PIEZO1 at the actomyosin cortex in myoblasts.

Research Use Only