MRP-L21 Polyclonal Antibody - BT-AP05578

MRP-L21 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP05578-20, BT-AP05578-50, BT-AP05578-100

Citations, Manuals and MSDS Available upon request.

Background: Mammalian mitochondrial ribosomal protein L 21 (39S ribosomal protein L21 mitochondrial) is encoded by nuclear gene MRPL21 and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Multiple transcript variants encoding different isoforms were identified through sequence analysis although some may be subject to nonsense-mediated decay (NMD).

Research Areas: Others

Target Protein: MRPL21

Applications: WB, IHC-p, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: MRP-L21 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 23159

UniProt Accession: Human: Q7Z2W9; Mouse: Q9D1N9

Synonyms: MRPL21; 39S ribosomal protein L21; mitochondrial; L21mt; MRP-L21

GeneID: Human: 219927; Mouse: 353242

Research Use Only