MRP-L3 Polyclonal Antibody - BT-AP05581

MRP-L3 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP05581-20, BT-AP05581-50, BT-AP05581-100

Citations, Manuals and MSDS Available upon request.

Background: Mammalian mitochondrial ribosomal protein L 3 (39S ribosomal protein L3 mitochondrial) is encoded by nuclear gene MRPL3 and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L3P ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 13q.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: MRPL3

Applications: WB, ELISA

Reactivity: Human

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: MRP-L3 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 38633

UniProt Accession: Human: P09001; Mouse: Q99N95

Synonyms: MRPL3; MRL3; RPML3; 39S ribosomal protein L3; mitochondrial; L3mt; MRP-L3

GeneID: Human: 11222

Research Use Only