MRP-L50 Polyclonal Antibody - BT-AP05595

MRP-L50 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP05595-20, BT-AP05595-50, BT-AP05595-100

Citations, Manuals and MSDS Available upon request.

Background: Mammalian mitochondrial ribosomal protein L 50 (39S ribosomal protein L50 mitochondrial) is encoded by nuclear gene MRPL50 and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a putative 39S subunit protein and belongs to the L47P ribosomal protein family. Pseudogenes corresponding to this gene are found on chromosomes 2p, 2q, 5p, and 10q.

Research Areas: Others

Target Protein: MRPL50

Applications: WB, ELISA

Reactivity: Human

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: MRP-L50 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 18325

UniProt Accession: Human: Q8N5N7; Mouse: Q8VDT9

Synonyms: MRPL50; 39S ribosomal protein L50; mitochondrial; L50mt; MRP-L50

GeneID: Human: 54534

Research Use Only