MRP-S22 Polyclonal Antibody - BT-AP05607

MRP-S22 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP05607-20, BT-AP05607-50, BT-AP05607-100

Citations, Manuals and MSDS Available upon request.

Background: 28S ribosomal protein S22 mitochondrial (mitochondrial ribosomal protein S22) is encoded by nuclear genes MRPS22 and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that does not seem to have a counterpart in prokaryotic and fungal-mitochondrial ribosomes. This gene lies telomeric of and is transcribed in the opposite direction from the forkhead box L2 gene. A pseudogene corresponding to this gene is found on chromosome Xq.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: MRPS22

Applications: WB, IHC-p, IF, ELISA

Reactivity: Human, Monkey

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: MRP-S22 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 41280

UniProt Accession: Human: P82650; Mouse: Q9CXW2

Synonyms: MRPS22; C3orf5; RPMS22; GK002; 28S ribosomal protein S22; mitochondrial; MRP-S22; S22mt

GeneID: Human: 56945

Research Use Only