Product Description

MRP-S22 (R263) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS3325-50, BS3325-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The mitoribosomes are composed of a 4:1 ratio of protein to RNA, with the proteins forming two subunits, the 28S subunit and the 39S subunit. Across species, the proteins that make up the mitoribosome subunits vary greatly in sequence, preventing easy recognition by sequence homology. MRP-S22 (mitochondrial 28S ribosomal protein S22), also known as S22mt, is a 360 amino acid mitochondrial ribosomal protein. Localized to the mitochondria, MRP-S22 is present in the 28S subunit of the mitoribosomes. Defects of MRP-S22 are the cause of combined oxidative phosphorylation deficiency type 5 (COXPD5). COXPD5 is an antenatal mitochondrial disease characterized by hypotonia, edema, cardiomyopathy and tubμlopathy.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: IHC, IF

Alternate Names: 28S ribosomal protein S22, mitochondrial, MRP-S22, S22mt, MRPS22, C3orf5, RPMS22, ORF Names: GK002

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 230-280 of Human MRP-S22.

Dilution: IHC: 1:50~1:200
IF: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: MRP-S22 (R263) polyclonal antibody detects endogenous levels of MRP-S22 protein.

Molecular Weight: ~ 41 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P82650

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only