MRP3 Polyclonal Antibody - BT-AP05564

MRP3 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP05564-20, BT-AP05564-50, BT-AP05564-100

Citations, Manuals and MSDS Available upon request.

Background: Canalicular multispecific organic anion transporter 2 (ATP binding cassette subfamily C member 3) encoded by ABCC3 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). Canalicular multispecific organic anion transporter 2 is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of Canalicular multispecific organic anion transporter 2 has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

Research Areas: Signal Transduction

Target Protein: ABCC3

Applications: WB, ELISA

Reactivity: Human

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: MRP3 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 169343

UniProt Accession: Human: O15438; Mouse: B2RX12

Synonyms: ABCC3; CMOAT2; MLP2; MRP3; Canalicular multispecific organic anion transporter 2; ATP-binding cassette sub-family C member 3; Multi-specific organic anion transporter D; MOAT-D; Multidrug resistance-a

GeneID: Human: 8714

Research Use Only