MRP6 Polyclonal Antibody - BT-AP11537

MRP6 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP11537-20, BT-AP11537-50, BT-AP11537-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene.

Research Areas: Metabolism; Signal transduction

Target Protein: ABCC6

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Multidrug resistance-associated protein 6

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: O95255; Mouse: Q9R1S7; Rat: O88269

Synonyms: Multidrug resistance-associated protein 6;ATP-binding cassette sub-family C member 6;Anthracycline resistance-associated protein;Multi-specific organic anion transporter E;MOAT-E

GeneID: Human: 368

Research Use Only