Product Description

MRP8 Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: AP0476-50, AP0476-100

Sizes: 50µl, 100µl

Swiss-Prot: P05109

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

Background: The family of EF-hand type Ca2+-binding proteins includes Calbindin (previously designated vitamin D-dependent Ca2+-binding protein), S-100 α and β, Cal-granulins A (also designated MRP8), B (also designated MRP14) and C (S-100 like proteins) and the parvalbumin family members, including parvalbumin α and parvalbumin β (also designated oncomodulin). Calbindin, S-100 proteins and parvalbumin proteins are each expressed in neural tissues. In addition, S-100 α and β are present in a variety of other tissues and Calbindin is present in intestine and kidney. Parvalbumin α is also found in fast-contracting/ relaxing skeletal muscle fibers and parvalbumin β is found in many tumor tissues as well as in the organ of Corti.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 101% (by SDS-PAGE).

Specificity: MRP8 polyclonal antibody detects endogenous levels of MRP8 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of MRP8 pAb at 1:500 dilution
Lane 1: PC12 whole cell lysate (40ug)
Lane 2: SP2/0 whole cell lysate (40ug)
Lane 3: EC9706 whole cell lysate (40ug)
Lane 4: A375 whole cell lysate (40ug)
Lane 5: HCC827 whole cell lysate (40ug), Immunohistochemistry (IHC) analyzes of MRP8 pAb in paraffin-embedded human breast carcinoma tissue at 1:100.

Bioworld Molecular Weight: ~ 23 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Protein S100-A8; Calgranulin-A; Calprotectin L1L subunit; Cystic fibrosis antigen; CFAG; Leukocyte L1 complex light chain; Migration inhibitory factor-related protein 8; MRP-8; S100 calcium-binding protein A8; Urinary stone protein band A; Protein S100-A8, N-terminally processed; S100A8; CAGA; CFAG; MRP8

Immunogen: Synthetic peptide, corresponding to amino acids CMGVAAHKKSHEESHKE of Human MRP8.

Conjugate: Unconjugated

Modification: Unmodified