MRPL22 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A24777-20, A24777-100
Citations, Manuals and MSDS Available upon request.
Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L22 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 4q. Two transcript variants encoding different isoforms have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human
Protein Weight: 13kDa/14kDa/23kDa
Observed Molecular Weight: 20kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 29093
SWISS: Q9NWU5
Alternate Names: MRPL22; HSPC158; L22mt; MRP-L22; MRP-L25; RPML25; mitochondrial ribosomal protein L22
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:1000 - 1:5000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics & Nuclear Signaling, Endocrine & Metabolism, Mitochondrial metabolism, Mitochondrial translation.
NCBI Alias: MRPL22
Research Use Only