MSH2 Monoclonal Antibody - BT-MCA4189

MSH2 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4189-50, BT-MCA4189-100

Citations, Manuals and MSDS Available upon request.

Background: This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: MSH2

Applications: WB, IHC, ICC, FCM

Clonality: Monoclonal

Clone ID: 2E2C7

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: MSH2

Immunogen: Purified recombinant fragment of human MSH2 (AA: 442-586) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 104.7kDa

UniProt Accession: P43246

Synonyms: FCC1, COCA1, HNPCC, LCFS2, hMSH2, HNPCC1

GeneID: 4436

Research Use Only