MSH2 Polyclonal Antibody - BT-AP05622

MSH2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP05622-20, BT-AP05622-50, BT-AP05622-100

Citations, Manuals and MSDS Available upon request.

Background: MSH2 is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E.coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: MSH2

Applications: IHC-p, IF, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: MSH2 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 104743

UniProt Accession: Human: P43246; Mouse: P43247; Rat: P54275

Synonyms: MSH2; DNA mismatch repair protein Msh2; hMSH2; MutS protein homolog 2

GeneID: Human: 4436; Mouse: 17685; Rat: 81709

Research Use Only