MSH6 Monoclonal Antibody-MB10335

MSH6 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10335-50, MB10335-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P52701

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-F, IHC-P, ICC/IF

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Background: The DNA mismatch repair system (MMR) repairs post-replication DNA, inhibits recombination between nonidentical DNA sequences, and induces both checkpoint and apoptotic responses following certain types of DNA damage. MSH2 (MutS homologue 2) forms the hMutS-α dimer with MSH6 and is an essential component of the mismatch repair process.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 153 kDa; Observed MW: 163 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of MSH6 in K562, C6, 3T3, Hela lysates using MSH6 antibody., Immunocytochemistry analysis of MSH6 in Hela using MSH6 antibody, and DAPI, Immunohistochemistry analysis of paraffin-embedded Human tonsil using MSH6 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: MSH6; GTBP; DNA mismatch repair protein Msh6; hMSH6; G/T mismatch-binding protein; GTBP; GTMBP; MutS-alpha 160 kDa subunit; p160

Immunogen: A synthetic peptide of human MSH6

Conjugate: Unconjugated

Modification: Unmodified