Product Description

MSH6 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB12133-50, MB12133-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P52701

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, ICC/IF, IP,

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Background: The DNA mismatch repair system (MMR) repairs post-replication DNA, inhibits recombination between nonidentical DNA sequences, and induces both checkpoint and apoptotic responses following certain types of DNA damage. MSH2 (MutS homologue 2) forms the hMutS-α dimer with MSH6 and is an essential component of the mismatch repair process.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 153 kDa; Observed MW: 163 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of MSH6 in A549, MCF-7, U251, C2C12 lysates using MSH6 antibody., Immunocytochemistry analysis of MSH6 in hela using MSH6 antibody, and DAPI

Alternative Name: MSH6; GTBP; DNA mismatch repair protein Msh6; hMSH6; G/T mismatch-binding protein; GTBP; GTMBP; MutS-alpha 160 kDa subunit; p160

Immunogen: A synthetic peptide of human MSH6

Conjugate: Unconjugated

Modification: Unmodified