MSI2 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS90884-50, BS90884-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q96DH6(Human) Q920Q6(Mouse) F1LWE6(Rat)
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, ICC IHC FC
All Applications: WB:1:500-1:1,000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100
Background: Msi2 (musashi homolog 2), also known as MSI2H, is a 328 amino acid protein that localizes to the cytoplasm and contains two RRM (RNA recognition motif) domains. Expressed ubiquitously at low levels, Msi2 functions as an RNA binding protein that, by regulating the expression of target mRNAs, is thought to play a role in the proliferation and maintenance of stem cells within the central nervous system. Msi2 is subject to post-translational phosphorylation and is upregulated in response to brain injury, suggesting a role in healing and brain tissue regeneration. Chromosomal aberrations involving the Msi2 gene are associated with the progression of chronic myeloid leukemia. Multiple isoforms of Msi2 exist due to alternative splicing events.
Purification and Purity: Protein affinity purified.
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: MSI2 polyclonal antibody detects endogenous levels of MSI2 protein.
Bioworld Molecular Weight: 35/37 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of MSI2 on SW480 (1) and K562 (2) cell lysate using anti-MSI2 antibody at 1/500 dilution., ICC staining MSI2 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Alternative Name: Musashi-2, MSI2, FLJ36569, MGC3245, Msi2, MSI2/HOXA9 fusion gene, included, MSI2H, MSI2H, Musashi 2, Musashi homolog 2, Musashi RNA binding protein 2, Musashi, Drosophila, homolog of, 2, Musashi-2, RNA binding protein Musashi homolog 2, RNA-binding protein Musashi homolog 2, WD 40 repeat protein MSI2,
Immunogen: Recombinant protein.
Conjugate: Unconjugated
Modification: Unmodified