Msx-2 rabbit pAb - ES6286

Msx-2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES6286-50, ES6286-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2. [provided by RefSeq, Jul 2008],

Alternate Name: MSX2; HOX8; Homeobox protein MSX-2; Homeobox protein Hox-8

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from the Internal region of human Msx-2.

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 28kD

Human Gene ID: 4488

Human SWISS Prot NO: P35548

Subcellular Location: Nucleus

Research Use Only