Product Description

MSX2 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS62390-50, BS62390-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Msx homeobox genes encode for transcription factors that control morphogenesis and are expressed at sites of epithelial-mesenchymal interaction during embryogenesis, such as the Tooth. Two of these genes, Msx-1 and Msx-2, are key factors for the development of tooth and craniofacial skeleton. Msx-1 also down-regμlates a master gene of skeletal cells differentiation. Msx-1 and Msx-2 contribute to the initial patterning of dentition as well as playing a pivotal role in terminal cell differentiation. In addition, Msx-1 and Msx-2 are expressed in the epidermis, hair follicles and fibroblasts of the developing fetal skin. In adμlt skin, Msx-1 and Msx-2 expression is confined to epithelially derived structures. Msx-2 is detected as a diffuse cytoplasmic signal in fetal epidermis and portions of the hair follicle and dermis, but is localized to the nucleus in the adμlt epidermis. Msx-1 and Msx-2 are also expressed during critical developmental stages of neural tube and neuralcrest, suggesting that these genes play an important role in organogenesis.

Category: Primary Antibody

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, IHC

Alternate Names: Homeobox protein MSX-2, Homeobox protein Hox-8, MSX2, HOX8

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to Human MSX2.

Dilution: WB:1:500~1:1000 IHC:1:50~1:200

Purification: The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).

Specificity: MSX2 polyclonal antibody detects endogenous levels of MSX2 protein.

Molecular Weight: ~ 34 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P35548

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.

Research Use Only