Product Description

MTERF Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS5804-50, BS5804-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Members of the mTERF family, including MTERF, MTERFD1, MTERFD2 and MTERFD3, are mitochondrial proteins that are believed to be transcription termination factors. MTERF (mitochondrial transcription termination factor 1) is composed of 399 amino acids and contains three leucine zippers that form a three-stranded coiled-coil that binds to DNA. It has been suggested that only the phosphorylated form of MTERF has transcription termination activity. MTERFD1 is also thought to act as a mitochondrial transcription regμlator and is expressed as two isoforms produced by alternative splicing. MTERFD3 is believed to be involved in cell cycle regμlation and cell growth by modμlating mitochondrial transcription. MTERFD3 is expressed in heart, skeletal muscle, pancreas and liver.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Transcription termination factor, mitochondrial, Mitochondrial transcription termination factor 1, mTERF, mTERF1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 311-356 of Human MTERF.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: MTERF polyclonal antibody detects endogenous levels of MTERF protein.

Molecular Weight: ~ 39, 45 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q99551

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only