MTERFD1 Monoclonal Antibody-MB9372

MTERFD1 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB9372-50, MB9372-100

Product: Mouse IgG1, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q96E29(Human) Q8R3J4(Mouse)

Host: Mouse

Reactivity: Human, Mouse

Applications: WB, IHC ICC

All Applications: WB:1:1,000-1:2,000
IHC:1:50-1:200
ICC:1:50

Background: MTERFD1 belongs to the MTERF family which consists of four members including MTERF1, MTERF2, MTERF3 and MTERF4. Previous research showed that MTERFD1 is a mitochondrial protein that interacts with the mitochondrial DNA promoter region and decreases transcription initiation in mammalian mitochondria. This negative regulation is likely important for fine-tuning mitochondria transcription in response to physiological demands. Human mitochondrial transcription termination factor domain 1 (MTERFD1) was mutated in many types of cancer. In vivo and in vitro data indicated that MTERFD1 gene possesses oncogenic properties.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: MTERFD1 monoclonal antibody detects endogenous levels of MTERFD1 protein.

Bioworld Molecular Weight: 48/38 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of MTERFD1 on different lysates using anti-MTERFD1 antibody at 1/1,000 dilution.
Positive control:
Lane 1: Hela
Lane 2: Mouse kidney tissue
Lane 3: K562, Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-MTERFD1 antibody. Counter stained with hematoxylin.

Alternative Name: mTERF3, MTERF3, MTERFD1, CGI-12, CGI 12, mitochondrial, Mitochondrial transcription termination factor 3, MTER1, MTERF domain containing 1, mTERF domain containing protein 1 mitochondrial, mTERF domain-containing protein 1, mTERF3, Mterfd1, Transcription termination factor 3, mitochondrial,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodified