MTHFR Polyclonal Antibody - BT-AP05643

MTHFR Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP05643-20, BT-AP05643-50, BT-AP05643-100

Citations, Manuals and MSDS Available upon request.

Background: Methylenetetrahydrofolate reductase encoded by MTHFR catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.

Research Areas: Signal Transduction; Metabolism

Target Protein: MTHFR

Applications: WB, ELISA

Reactivity: Human, Mouse, Monkey

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: MTHFR Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 74597

UniProt Accession: Human: P42898; Mouse: Q9WU20

Synonyms: MTHFR; Methylenetetrahydrofolate reductase

GeneID: Human: 4524; Mouse: 17769

Research Use Only