MTHFR rabbit pAb - ES2863

MTHFR rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES2863-50, ES2863-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene catalyzes the conversion of 5, 10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.[provided by RefSeq, Oct 2009],

Alternate Name: MTHFR; Methylenetetrahydrofolate reductase

Source: Rabbit

Applications: WB; ELISA; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Reactivity: Human; Mouse; Monkey

Immunogen: The antiserum was produced against synthesized peptide derived from human MTHFR. AA range:314-363

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 75kD

Human Gene ID: 4524

Human SWISS Prot NO: P42898

Subcellular Location: cytosol, synapse,

Research Use Only