MTNR1A Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A27759-20, A27759-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Rat
Protein Weight: 39kDa
Observed Molecular Weight: 40kDa/45kDa
Immunogen: Synthetic peptide .
Species: Human
GeneID: 4543
SWISS: P48039
Alternate Names: MT1; MEL-1A-R
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:1000 - 1:6000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, G protein signaling, G-Protein-Coupled ReceptorsGPCR, Endocrine Metabolism, Neuroscience.
NCBI Alias: MTNR1A
Research Use Only