mtTFA Polyclonal Antibody-BS90890

mtTFA Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90890-50, BS90890-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q00059(Human)

Host: Rabbit

Reactivity: Human

Applications: WB, ICC/IF, IHC, IP

All Applications: WB:1:200-1:500
ICC/IF:1:50-1:200
IHC:1:50-1:200
IP:1:10-1:50

Background: Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind and bend DNA. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA. target DNA. Interacts with TFB1M and TFB2M.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: mtTFA polyclonal antibody detects endogenous levels of mtTFA protein.

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodified

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of mtTFA on Hela cell using anti-mtTFA antibody at 1/1,000 dilution., ICC staining mtTFA in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.