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MUC4 Polyclonal Antibody - E-AB-91656

MUC4 Polyclonal Antibody - E-AB-91656

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MUC4 Polyclonal Antibody Sizes: 60μL, 120μL, 200μL Catalogue Numbers: E-AB-91656-60, E-AB-91656-120, E-AB-91656-200 Citations, Manuals and MSDS Available upon request. Abbreviation: MUC4 Target Synonym: MUC4; ASGP; HSA276359; MUC-4; mucin-4 Conjugation: Unconjugated Host: Rabbit Species Reactivity: Human Application: WB Isotype: IgG Clonality: Polyclonal UNIProt ID: Q99102 Background: The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. This gene encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. At least two dozen transcript variants of this gene have been found, although for many of them the full-length transcript has not been determined or they are found only in tumor tissues. This gene contains a region in the coding sequence which has a variable number (>100) of 48 nt tandem repeats. Concentration: 1mg/mL Immunogen: A synthetic peptide of human MUC4 Buffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3. Purification Method: Affinity purification Dilution: WB 1:500-1:2000 Calculated MW: 112-130kDa/144kDa/194-231kDa Observed MW: 540KDa Storage: -20°C/One year. Avoid freeze / thaw cycles. Shipping: Ice bag Research Use Only