MUL1 rabbit pAb - ES10762

MUL1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES10762-50, ES10762-100

Citations, Manuals and MSDS Available upon request.

Background: domain:The zinc finger domain is required for E3 ligase activity., function:E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates., pathway:Protein modification; protein ubiquitination., similarity:Contains 1 RING-type zinc finger., subcellular location:Transported in mitochondrion-derived vesicles from the mitochondrion to the peroxisome., subunit:Homooligomer. Interacts with MAP3K7/TAK1., tissue specificity:Widely expressed with highest levels in the heart, skeletal muscle, placenta, kidney and liver. Barely detectable in colon and thymus.,

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from part region of human protein

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 38kD

Human Gene ID: 79594

Human SWISS Prot NO: Q969V5

Subcellular Location: Mitochondrion outer membrane; Multi-pass membrane protein. Peroxisome. Transported in mitochondrion-derived vesicles from the mitochondrion to the peroxisome.

Research Use Only