Musashi-1 Monoclonal Antibody-MB0154

Musashi-1 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB0154-50, MB0154-100

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: O43347

Host: Mouse

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:1000

Background: This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13.RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5´-GUUAGUUAGUUAGUU-3´ and other sequences containing the pattern 5´-[GA]U1-3AGU-3´. May play a role in the proliferation and maintenance of stem cells in the central nervous system.

Purification and Purity: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This antibody detects endogenous levels of Musashi-1 and does not cross-react with related proteins

Bioworld Molecular Weight: Predicted band size:39KDa
Observed band size:39KDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western BlotDetection of MSI1 in U87MG, C6, IMR32, mouse brain&PC12 cell lysates and using MSI1 antibody (1:1000 diluted).

Alternative Name: RNA-binding protein Musashi homolog 1; Musashi-1; MSI1

Immunogen: Recombinant full length Human Musashi-1.

Conjugate: Unconjugated

Modification: Unmodified