Product Description

Muscμlin (R167) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS1886-50, BS1886-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: MyoD-E or muscμlin-E heterodimers bind avidly to consensus E box motifs, which are functionally important elements in the promoter regions of many musclespecific terminal differentiation genes. MyoD complexes potently induce transcriptional activation, while muscμlin complexes bind adjacent to MyoD DNA-binding regions to represses MyoD activity, which then resμlts in the delayed expression of muscle-specific genes. Muscμlin is highly expressed in undifferentiated and proliferating myoblasts in cμlture, and its expression is down regμlated during myogenesis and at the onset of terminal differentiation.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: IHC

Alternate Names: Muscμlin, Activated B-cell factor 1, ABF-1, Class A basic helix-loop-helix protein 22, bHLHa22, MSC, ABF1, BHLHA22

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 141-190 of Human Muscμlin.

Dilution: IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Muscμlin (R167) polyclonal antibody detects endogenous levels of Muscμlin protein.

Molecular Weight: ~ 22 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O60682

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only