Muscle actin mouse Monoclonal Antibody (4G10) - BT-MCA0909

Muscle actin mouse Monoclonal Antibody (4G10)

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-MCA0909-20, BT-MCA0909-50, BT-MCA0909-100

Citations, Manuals and MSDS Available upon request.

Background: The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.

Research Areas: Signal transduction; Stem cells; Developmental biology; Cardiovascular

Target Protein: ACTA1

Applications: IHC-p, IF

Reactivity: Human,Rat,Mouse

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: ACTA1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P68133; Mouse: P68134; Rat: P68136

Synonyms: ACTA1

GeneID: Human: 58

Research Use Only