MuSK (phospho Tyr755) rabbit pAb - ES6294

MuSK (phospho Tyr755) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES6294-50, ES6294-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a muscle-specific tyrosine kinase receptor. The encoded protein may play a role in clustering of the acetylcholine receptor in the postsynaptic neuromuscular junction. Mutations in this gene have been associated with congenital myasthenic syndrome. Alternatively spliced transcript variants have been described.[provided by RefSeq, Oct 2009],

Alternate Name: MUSK; Muscle; skeletal receptor tyrosine-protein kinase; Muscle-specific tyrosine-protein kinase receptor; MuSK; Muscle-specific kinase receptor

Source: Rabbit

Applications: WB; ELISA; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized phospho-peptide around the phosphorylation site of human MuSK (phospho Tyr755)

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 97kD

Human Gene ID: 4593

Human SWISS Prot NO: O15146

Subcellular Location: Cell junction, synapse, postsynaptic cell membrane; Single-pass type I membrane protein. Colocalizes with acetylcholine receptors (AChR) to the postsynaptic cell membrane of the neuromuscular junction.

Research Use Only