MutS Protein Homolog 6 (MSH6) Monoclonal Antibody
Sizes: 100μL, 200μL
Catalogue Numbers: PA6196-100, PA6196-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: MutS Protein Homolog 6(MSH6)
Target Synonym: MSH2, COCA1, FCC1, HNPCC, HNPCC1, LCFS2
Conjugation: Unconjugated
Host: Mouse
Species Reactivity: Human
Application: IHC-P
Clonality: Monoclonal
Clone No.: YN01136m
UNIProt ID: P43246
Background: MSH6, known as MutS homolog 6 (E.coli), is a mismatch repair gene. DNA mismatch repair is very necessary to maintain the integrity of genetic information. The change of microsatellite's reproducibility is caused by the slippage of the hinge misalignment during DNA replication, which is also called microsatellite instability. Mutant mismatch repair proteins are often expressed in patients with high frequency microsatellite instability (MSI-H), which is related to autosomal dominant inheritance, also known as hereditary nonpolyposis colorectal cancer (HNPCC), and sporadic (MSI-H) colorectal cancer. MLH1, MSH2, MSH6 antibodies can be used to screen the disease in patients and their families.
The concentrated should be stored at -20°C protecting from light,The RTU should be stored at 2~8°C protecting from light (Do not freeze).Valid for 12 months.
Shipping: Ice bag
Research Use Only