MUTYH Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-10477-60, E-AB-10477-120, E-AB-10477-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: MUTYH
Target Synonym: A/G specific adenine DNA glycosylase; A/G-specific adenine DNA glycosylase; Adenine DNA glycosylase; CYP2C; hMYH; MGC4416; MutY (E. coli) homolog; MutY homolog (E. coli); MutY homolog; MutY; E. coli; homolog of; Mutyh; MUTYH; MYH; rMYH
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human
Application: WB, IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q9UIF7
Background: This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7, 8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Concentration: 0.3 mg/mL
Immunogen: Recombinant protein of human MUTYH
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:1000-1:5000, IHC 1:50-1:200
Calculated MW: 60kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only