MVK (N175) Polyclonal Antibody-BS2296

MVK (N175) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS2296-50, BS2296-100

Sizes: 50µl, 100µl

Swiss-Prot: Q03426

Host: Rabbit

Reactivity: Human

Applications: WB, IHC, IF

Background: Mevalonate kinase (MVK) is an early enzyme in isoprenoid and sterol synthesis. Mevalonate kinase catalyzes the ATP-dependent phosphorylation of mevalonic acid to form mevalonate 5-phosphate. Deficiency in MVK activity contributes to mevalonic aciduria and hyperimmunoglobulinemia D/periodic fever syndrome (HIDS).

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: MVK (N175) polyclonal antibody detects endogenous levels of MVK protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of MVK (N175) pAb at 1:500 dilution
Lane 1: PC3 whole cell lysate (20ug)
Lane 2: HepG2 whole cell lysate (40ug)
Lane 3: MCF-7 whole cell lysate (40ug), Immunohistochemistry (IHC) analyzes of MVK (N175) pAb in paraffin-embedded human brain tissue.

Bioworld Molecular Weight: ~ 42 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Mevalonate kinase; MK; KIME

Immunogen: Synthetic peptide, corresponding to amino acids 150-200 of Human MVK.

Conjugate: Unconjugated

Modification: Unmodified