MVK Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-11414-60, E-AB-11414-120, E-AB-11414-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: MVK
Target Synonym: FLJ96772; KIME; LH receptor mRNA binding protein; LRBP; Mevalonate kinase 1; Mevalonate kinase; Mevalonic aciduria; MK; mvk; MVLK; POROK3
Research Areas: Cancer, Cardiovascular, Metabolism, Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: WB, IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q03426
Background: This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash.
Concentration: 0.4 mg/mL
Immunogen: Recombinant protein of human MVK
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:200-1:1000, IHC 1:100-1:300
Calculated MW: 42kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only