Product Description

MVP Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90899-50, BS90899-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: O94760(Human)

Host: Rabbit

Reactivity: Human

Applications: WB, IHC, IP

All Applications: WB:1:500-1:2,000
IHC:1:50-1:200

Background: DDAH, a dimethylarginine dimethylaminohydrolase, hydrolyzes dimethyl arginine (ADMA) and monomethyl arginine (MMA), both inhibitors of nitric oxide synthases, and may be involved in in-vivo modulation of nitric oxide production. Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation. DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA). DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: MVP polyclonal antibody detects endogenous levels of MVP protein.

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodified

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of DDAH1 on human kidney (1) and human liver (2) tissue lysate using anti-DDAH1 antibody at 1/1,000 dilution., Immunohistochemical analysis of paraffin-embedded human prostate tissue using anti-DDAH1 antibody. Counter stained with hematoxylin.